Safe chemotherapy and targeted therapy for treating locally advanced NPC in a G6PD-deficient patient: case report and literature review
Authors
Abstract:
The article was first report a case of a 32-year-old female with NPC that is G6PD-deficient. The patient completed induction chemotherapy and concomitant chemoradiotherapy successfully. The patient experienced grade 1 neutropenia , grade 1 diarrhea, and grade 2 acne-like skin reactions during the three cycles of induction chemotherapy. Grade 1 neutropenia, grade 1 diarrhea, grade 2 oral mucositis and grade 1 skin reactions were observed during the concomitant chemoradiotherapy. No hemolytic events were observed. We conclude that it is safe for G6PD-deficient patients with NPC to received chemotherapy and targeted therapy.
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Journal title
volume 17 issue 3
pages 497- 500
publication date 2019-06
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